Dr. Constance Peterson (Ingrid Bergman) is a staff psychiatrist at Green Manors mental hospital. Among her colleagues she is seen as a repressed woman with walls around her. But upon the retirement of the chief of staff at the hospital and the coming of his replacement Dr. Anthony Edwardes (Gregory Peck), she finds herself undeniably attracted to the new man. At first she pretends to be only interested in psychiatry but it quickly develops into a romantic attraction. Fortunately, being so close to him, she begins to realize he is not really Dr. Edwardes before anyone else discovers. She diagnoses him with amnesia. But because the real Dr. Edwardes is discovered dead, she realizes she must flee with him to uncover his true identity and clear him of suspicion of being a murderer.